منابع مشابه
Regulation of Bone Metabolism
Bone is formed through the processes of endochondral and intramembranous ossification. In endochondral ossification primary mesenchymal cells differentiate to chondrocytes and then are progressively substituted by bone, while in intramembranous ossification mesenchymal stem cells (MSCs) differentiate directly into osteoblasts to form bone. The steps of osteogenic proliferation, differentiation,...
متن کاملregulation of bone metabolism
bone is formed through the processes of endochondral and intramembranous ossification. in endochondral ossification primary mesenchymal cells differentiate to chondrocytes and then are progressively substituted by bone, while in intramembranous ossification mesenchymal stem cells (mscs) differentiate directly into osteoblasts to form bone. the steps of osteogenic proliferation, differentiation,...
متن کاملHypothalamic regulation of energy homeostasis
Introduction For many years obesity has been known to induce a state of systemic low-grade inflammation that contributes to the development of numerous comorbidities, such as type 2 diabetes, dyslipidemia, cardiovascular diseases, and neurodegenerative disorders (1–3). In addition to metabolic derangements in peripheral organs, obesity-related inflammatory changes perturb brain function, especi...
متن کاملRegulation of GNRH production by estrogen and bone morphogenetic proteins in GT1-7 hypothalamic cells.
Recent studies have shown that bone morphogenetic proteins (BMPs) are important regulators in the pituitary-gonadal endocrine axis. We here investigated the effects of BMPs on GNRH production controlled by estrogen using murine GT1-7 hypothalamic neuron cells. GT1-7 cells expressed estrogen receptor alpha (ERalpha; ESR1 as listed in MGI Database), ERbeta (ESR2 as listed in MGI Database), BMP re...
متن کاملObesity: Hypothalamic Regulation of Food Intake
Obesity etiology encompasses several factors; many of which are related with nutrition and behavioral disorders, endocrine alterations, drug use, neurologic and genetic diseases. The intriguing “fat epidemic”, with its staggering ever-growing numbers, has been the focus of speculation regarding the true reasons for its expansion, since sedentary lifestyle and changes in diets with fat intake al...
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ژورنال
عنوان ژورنال: Journal of Molecular Endocrinology
سال: 2010
ISSN: 0952-5041,1479-6813
DOI: 10.1677/jme-10-0015